产品货号：
Z20774
中文名称：
MTBP抗体
英文名称：
Anti-MTBP Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-MTBP Antibody |
| 指标别名 | hMTBP;Mdm2 binding protein;MDM2BP;MTBP |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | ELISA,WB,ICC,IF |
| 基因名称 | MTBP |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | MTBP antibody was raised against a 18 amino acid peptide near the center of human MTBP.The immunogen is located within amino acids 110 - 160 of MTBP. |
| 计算分子量 | 102kDa |
| 成分 | MTBP Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | MTBP Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | The p53 tumor-suppressor gene integrates numerous signals that control cell life and death.Several novel molecules involved in p53 network,including Chk2,p53R2,p53AIP1,Noxa,PIDD,PID/MTA2 and MTBP,were recently discovered.The transcriptional activity of p53 is modulated by posttranslational regulations of the p53 protein including stabilization and acetylation.P53 transcriptionally activates MDM2 gene then the translated MDM2 protein binds to p53 and promotes the degradation of p53 leading to lowering the concentration of p53 protein.MDM2 inhibits both p53 mediated G1 arrest and apoptosis.A recently discovered protein termed MTBP was found to bind to MDM2 and to inhibit the modulation effect of MDM2 on p53.MTBP is expressed in a variety of normal tissues. |
| Uniprot ID | Q96DY7 |
| 基因名全称 | Mdm2,transformed 3T3 cell double minute 2,p53 binding protein (mouse) binding protein,104kDa |
| 蛋白名全称 | Mdm2,transformed 3T3 cell double minute 2,p53 binding protein (mouse) binding protein,104kDa |
| 推荐稀释比 | MTBP antibody can be used for detection of MTBP by Western blot at 1 to 2μg/mL.A 104kDa band can be detected.Antibody can also be used for immunocytochemistry starting at 5μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in human samples;Immunocytochemistry in human samples and Immunofluorescence in human samples.All other applications and species not yet tested. |
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